Isabelle Stévant

Ph.D in Bioinformatics

Post-doctotal fellow
Bar Ilan University
Israel

Biography

I am a researcher in developmental biology, focussing in sex determination in mice.

I design and conduct cutting edge -omics experimental and computational approaches from the bench to the data analysis. My research interest is to understand how gene expression is regulated during cell fate decision and maintained during embryonic development and organogenesis. I am particularly interested in sex determination and gonadal development as it represents a unique model of cell fate decision where cells can adopt two opposite identities (testicular or ovarian) and are capable to transdifferentiate between the two fates even in adult upon genetic perturbation. I am applying molecular genetics and bioinformatics analysis to decipher the link between the chromatin landscape and the dynamic of gene expression driving cell fate decision and the maintenance of cellular identity.

Education

2018	Doctorat ès science in bioinformatics, University of Geneva, Switzerland. Ph.D manuscript
2011	M.Sc. in bioinformatics, Université de Rennes 1, France.
2019	B.Sc. in biology, Université de Rennes 1, France

Employment history

From 2022	Post-doctoral fellow. Reconstruction of the gene regulatory network driving mouse gonadal sex determination through multi-omics data integration. Dr. Nitzan Gonen Lab, Bar Ilan University, Ramat Gan, Israel.
2019-2021	Post-doctoral fellow. High-resolution spatiotemporal enhancer-reporter assay during Drosophila melanogaster embryonic development. Dr. Yad Ghavi-Helm Team, CNRS UMR 5242, IGFL-ENS Lyon, France.
2013-2018	Ph.D student. Monitoring gonadal somatic cell differentiation during sex determination using single-cell RNA sequencing. Prof. Serge Nef Lab & Prof. Manolis Dermitzakis lab, Department of Genetics Medicine and Development, University of Geneva, Switzerland.
2011-2013	Front-end developer. European project EHR4CR (Electronic Health Record for Clinical Research). Conception and implementation of a web-service centralised platformto recruite and monitor patients for European scale clinical trials. Medical informatics team, UMR 936, Université de Rennes 1, France.

Contact

Coming soon...